A different approach for difficult transcription factor targets.
LC Scientific works with researchers studying transcription factors that have produced weak, inconsistent, or failed results with conventional ChIP-seq approaches. Our BFPX platform provides an alternative crosslinking strategy designed for these challenging targets.
Many transcription factors remain difficult to study because crosslinking efficiency can vary substantially across protein–DNA interactions. BFPX-ChIP is designed to provide an alternative approach for targets that are poorly captured using conventional formaldehyde crosslinking.
A specialized approach for transcription factors that are difficult to capture using conventional ChIP-seq workflows.
Each project is tailored to the transcription factor, experimental system, and available prior data.
Scientific collaboration from initial consultation through project design, sequencing, and data delivery.
Project design and feasibility are determined during consultation.
Have a challenging ChIP target?
Let’s discuss your target, experimental system, and previous results to determine whether BFPX-ChIP may be a good fit.